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Test Code CBCD Complete Blood Count (CBC) with Automated Differential

Container

Purple

Specimen Stability

2 days

Rejection Reasons

Clotted
Frozen

Reference Range

 

0-2 Months

2 M to 1 year

1 year to 15 years

 

15 Y & older

WBC

5.0 - 38.0 x 10^3 / uL

5.0 - 18.0

4.5 - 12.0

 

4.8 - 10.8

RBC

3.90 - 7.10 x 10^6/uL

3.80 - 6.00

3.80 - 5.50

 

F: 4.20 - 5.40
M: 4.70 - 6.10

Hgb

12.0 - 27.0 g/dL

9.0 - 18.0

9.0 - 16.5

 

F: 12.0 - 16.0
M: 14.0 - 18.0

Hct

43.0 - 61.0%

35.0 - 45.0%

35.0 - 40.0%

 

F: 37.0 - 47.0%
M: 42.0 - 52.0%

MCV

91 - 120 fL

77 - 93 fL

77 - 85 fL

 

F: 81 - 99 fL
M: 80 - 90 fL

MCH

35 - 38 pg

25 - 35 pg

27 - 31 pg

MCHC

33 - 37 g/dL

33 - 36 g/dL

33 - 37 g/dL

Platelet

140 - 350 x 10^3/uL

RDWSD

39 - 50 fL

RDWCV

11.5 - 14.5%

MPV

7.4 - 12.2 fL

 

 

 

 

 

 

 

0-2 Months

2 M to 3 years

3 Y to 9 Y

9 Y to 15 Y

15 Y & Older

Neut %

40 - 75%

30 - 40%

35 - 60%

45 - 60%

50 - 80%

Neut #

2.5 - 7.5 x 10^3 / uL

Lymph %

20 - 45%

40 - 60%

35 - 55%

20 - 35%

10 - 50%

Lymph #

1.0 - 4.0 x 10^3/uL

Mono %

5 - 15%

Mono #

0.05 - 0.6 x 10^3/uL

Eos %

0 - 8%

Eos #

0.05 - 0.5 x 10^3/uL

Baso %

0 - 1%

Baso #

0.0 - 0.1 x 10^3/uL

IG %

0 - 5%

IG #

0.0 - 0.5 x 10^3/uL

 

Critical Value

Hgb: <7.0 g/dL

Hct: <21.0%

WBC: <1.5 or >30.0 x 10^3/uL

Platelets: <35 or >1,499 x 10^3/uL

CptCode

85025

Reflex Testing

  • Manual Differential if flagged by analyzer
  • Peripheral Smear review sent to Pathology if one or more of the following criteria are met:
  • Based on CBC Results

    • WBC count greater than 30,000
    • RBC greater than 6.5 for male or greater than 6.0 for female
    • Hemoglobin less than 6.0 or greater than 18.0
    • Platelet count less than 35 or greater than 1000
    • MCV less than 60 or greater than 110 for adult

    Based on Absolute Numbers

    • Neutrophils less than 0.5
    • Lymphocytes greater than 7 (over 14 years); greater than 10 (1-14 years)
    • Monocytes greater than 3
    • Eosinophils greater than 2
    • Basophils greater than 0.5

    Based on Manual Differential

    • Blasts, unclassifiable – any
    • Promyelocytes greater than 3
    • Myelocytes greater than 5
    • Metamyelocytes greater than 10
    • NRBC (per 100 WBC) greater than 3
    • Any unusual or questionable hematological findings that one or more techs are not confident in classifying.

    New Significant RBC Morphologic Abnormalities

    • 3+: anisocytosis, poikilocytosis, elliptocytes, hypochromia, polychromasia, basophilic stippling, stomatocytes
    • 2+: target cells, rouleaux
    • 1+: schistocytes, spherocytes, acanthocytes, tear drop cells
    • Any: sickle cells, Howell Jolly bodies, Pappenheimer bodies, agglutination, intraerythrocytic organisms

    New Significant WBC Morphologic Abnormalities

    • 3+: Dohle bodies
    • 2+: hyposegmented PMNs
    • 1+: hypersegmented, hypogranular PMNs
    • Any: Auer Rods

    Platelet Morphologic Abnormalities

    • 2+: giant, agranular platelets
    • 1+: bizarre platelets, satellitosis

    When Ordered by a Provider

    • If the CBC has not been performed at MHCC, perform a CBC on the hematology analyzer.
    • If only slides have been sent from the ordering provider, contact testing location for copy of instrument print-out.

    Newborn Criteria

    • Hemoglobin less than 14.0
    • MCV less than 85
    • Lymphocyte absolute count greater than 14
    • Nucleated RBC greater than 50 for patients less than 7 days old

    Frequency of Path Review

    Patients with chronic problems that have values that repeatedly fall within these criteria need only be reviewed by a pathologist one time in each 180-day period, unless a distinct change occurs.